Why does this popular plan work? For one thing, it pushes wildly healthy staples to the forefront (think: nuts, vegetables, fruit, olive oil). For another, it's simply delicious, thanks to it's focus on fresh, simply prepared dishes like grilled fish with lemon and whole wheat pita with hummus. Science agrees: One meta-review of 16 studies, found the eating M.O. helped those on it lose an average of 8.5 pounds.
Another way to trim carbs and calories and lose weight fast is by making your sandwich open-faced. Opting for one slice of bread instead of two will save you 70-90 calories, and leaves you more room to pile it high with healthy toppings like lettuce, tomato, sprouts, and avocado. Still hungry? Pair your sandwich with a side of baby carrots or bell pepper strips. The water and fiber in the veggies will fill you up and help with your weight-loss efforts.
So how does this work? A quick run-through: The first tip was to eat low carb. This is because a low-carb diet lowers your levels of the fat-storing hormone insulin, allowing your fat deposits to shrink and release their stored energy. This tends to cause you to want to consume fewer calories than you expend – without hunger – and lose weight. Several of the tips mentioned above are about fine-tuning your diet to better this effect.
Build muscle. Muscle burns more calories than fat. So adding strength training to your exercise routine can help you reach your weight loss goals as well as give you a toned bod. And weights are not the only way to go: Try resistance bands, pilates, or push-ups to get strong. A good, well-balanced fitness routine includes aerobic workouts, strength training, and flexibility exercises.
“This is a great way of eating that I highly recommend to many clients, and I even model in my own life,” says Elizabeth Shaw, RDN, who is in private practice in San Diego and is the co-author of Fertility Foods Cookbook. “Since the premise of the diet is designed to help people who have high blood pressure, low-sodium foods are recommended. But considering that most Americans exceed their daily sodium levels anyway, it’s not surprising that dietitians recommend this style of eating for treating many different conditions, such as heart disease and obesity.”
Like a marathoner stretching before the big run, eating half a grapefruit before a meal can enhance your body’s fat-burning performance. A study published in the journal Metabolism found that this “warm-up” tactic can help whittle your middle—by up to an inch—in just six weeks! The scientists attribute the powerful effects to the grapefruits’ fat-zapping phytochemicals. The fruit can interact negatively with certain medications, so as long as you get the green-light from your M.D, plan to have half of a grapefruit before your morning meal and add a few segments your starter salads to reap the benefits.

Losing weight is hard. Losing weight and then keeping it off is even harder. Case in point: 74% of adults in the United States are overweight or obese, and weight loss is a $20 billion industry. All that said, if you're trying to slim down, there's no reason to lose hope. Plenty of studies show that lasting weight loss is not a myth. Work some of the 57 research-backed food, exercise, and lifestyle tips that follow into your routine, and watch the pounds start to come off.
What's more trustworthy than a diet built by experts from the Mayo Clinic? Created by doctors, nutritionists, and all-star chefs, the plan has a few phases: In the first, you should lose 6 to 10 pounds in two weeks. After that, you can expect to lose 1 to 2 pounds a week until you reach your goal weight. You're also given plenty of resources and advice to help you keep the weight off.
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