Where commercial weight loss programs go hands-on, the Mayo Clinic Diet goes streamlined. The vibrant, best-selling hardback (that looks a lot like a fun middle school health textbook) is the first resource for diet information, you can also employ the sleekly designed but minimalist app, plus a full website of tips, recipes, and workouts. Those patient enough to cycle through all of Mayo’s resources will find lots of solid health information.
Given that all participants in the study were overweight and “healthy”, what was not studied, and could have been very useful, was what was the impact of the two diets on participants’ blood sugars (HbA1c), insulin levels, and on some measure of inflammation. It is possible that there could have been little difference in weight loss between the two diets but big differences in the impact on risk factors related to diabetes.
The data behind its efficacy is strong; according to a systematic meta-analysis of scientific studies published in 2004 in the American Journal of Clinical Nutrition, a 3×120 mg per day dose of orlistat nearly doubles the likelihood that you’ll achieve what doctors deem “clinically significant” weight loss over the course of a year on the supplement. This amounts to ten percent of your body mass (2).
Stopping eating after dinner is an easy way to easily cut back on mindless munching and extra calories, and can help boost weight loss, White says. One way to prevent that post-dinner grazing is to brush your teeth almost immediately after your last meal of the day. The minty flavor in your mouth will make all your favorite foods taste gross anyway, and you won’t want to go back and brush your teeth all over again.
You might feel silly, but it works. When Alan R. Hirsch, MD, neurological director of the Smell & Taste Treatment and Research Foundation in Chicago, tried this with 3,000 volunteers, he found that the more frequently people sniffed, the less hungry they were and the more weight they lost—an average of 30 pounds each. One theory is that sniffing the food tricks the brain into thinking you’re actually eating it.
Sure, there's your one friend who swears by the Taco Cleanse. And that other friend who ate nothing but broccoli soup for a month and dropped 20 pounds, found the love of her life, and got promoted at work. But before you start blending 80 stalks of broccoli into a cup or crunching your way through a crate of tacos, check out which diets are backed by science. Because don't you want to try one that will do the trick for you?